Pet Wellbeing Milk Thistle for Cats - Supports Liver Health, Protects Liver - Glycerin-Based Natural Herbal Supplement - 2 oz (59 ml)

Product Information

In conclusion, despite the wide presence of commercially available complementary feed to support liver function in dogs and cats and their widespread usage, studies on that topic (on molecules previously discussed) and on such species are rather scarce, while on the other hand, numerous studies have been carried out both in humans and in laboratory animals. Complementary feeds may represent a help in managing liver diseases in pets, but additional research studies are needed to confirm or exclude the presence of beneficial effects in different pathological conditions, including studies concerning the titration of active ingredients. Conflicts of Interest Recently a senior kitty of our’s needed to go on Denamarin Advanced to try and get his liver numbers improved. This senior fellow does not like any medication, in any form, of any taste…lol. You can’t hide it in his food – wet or dry – and he will fight/squirm to the max if you try to pill him. Free radicals are unstable atoms that roam the body, causing damage to cells. Antioxidants acting as free radical scavengers have the ability to bind these atoms and deactivate them. Many compounds in nature can act as antioxidants. Habib, R. (n.d.) Milk thistle for your dog. Dogs Naturally Magazine. Retrieved 2/7/2020 from https://www.dogsnaturallymagazine.com/milk-thistle-for-your-dog/

To assess the possible efficacy of nutraceuticals on liver diseases, studies on cell cultures have also been carried out on single molecules/complexes or on their combination, with not always concordant results. A recent study reports the effects of a pretreatment with the combination of S-adenosylmethionine and silybin on primary canine hepatocytes exposed to the proinflammatory cytokine IL-1 β, and these molecules are hypothesized as a possible support to the liver function. Indeed, the presence of this combination was associated with reduced levels of PGE 2, IL-8, and macrophage chemotactic protein-1 (proinflammatory molecules induced by IL-1 β administration) as well as to higher glutathione (GSH) levels (reduction of oxidative stress) [ 20]. Similarly, a previous study by the same authors reported the efficacy of silybin and of a silybin-phosphatidylcholine complex in canine primary hepatocyte cultures exposed to IL-1 β, as demonstrated by a significant reduction of proinflammatory markers (PGE 2, IL-8, and monocyte chemotactic protein-1) and by a decreased NF- κB nuclear translocation, for the silybin-phosphatidylcholine complex [ 22]. On the other hand, in a study on cultured canine hepatocytes, the exposition to silibinin and simultaneously to α-amanitin, a known liver toxin from amanitin containing mushrooms (e.g. Amanita phalloides), did not show protective effects on those cells, which are measured by hepatocytes viability and lactate dehydrogenase activity measurement [ 21]. 3.2. S-Adenosylmethionine (SAMe) Milk Thistle may also be beneficial to cats undergoing chemotherapy as Silymarium may enhance the activity of certain chemo drugs. Denamarin helps to protect liver cells from toxins and inflammatory damage, and improves liver function.Full-Spectrum Extract: The full biochemical spectrum of the herbs is preserved to ensure the potency of the extract. All raw materials are tested for identification and purity. Twedt, D.C. (n.d.). Emerging newer liver conditions to be aware of in the dog. Colorado State University. Retrieved 2/6/2020 from https://pdfs.semanticscholar.org/96da/d6174658dc6fe146ad9115b6fceb30027c5c.pdf

Do NOT sprinkle milk thistle on food. Get empty gel caps (size 0) at a health food store, put the amount you want to give in a gel cap, coat the gel cap lightly with butter and pill him with it. For about three weeks now this has yielded about 95% success on the first try. A few times he’s super sneaky and spit it out…lol. Research has shown dogs with ascites (the accumulation of fluid in the peritoneal cavity) treated with silymarin along with supportive therapy were able to attain normal activities after 45 days of therapy indicating the effectiveness of silymarin on hepatic dysfunction ( 9). Ascites is most often caused by liver scarring such as in cirrhosis. Milk Thistle for dogs and cats is a key natural ingredient to support elderly pets due to its multi-health benefits. You can read Peachez's Story with Milk Thistle for cats and how it helped her with cancer and liver problems.

Conclusion

Milk thistle for dog liver support can be used in conjunction with conventional treatments and is glycerin based and safe for long-term use. You can read more about the benefits of using milk thistle on Dr. Hillary Cook’s blog. Milk Thistle is a safe herb that is well tolerated by your pet. It is herb that is recommend and used by holistic practitioners All NHV Natural Pet Products are pure herbal extracts and contain no artificial additives, preservatives or coloring. Shelf life after opening is 6 months and must be refrigerated after opening. Kazazis, C., Evangelopoulos, A.A., Kollas, A., and Vallianou, N.G. (2014). The therapeutic potential of milk thistle in diabetes. Rev Diabet Stud, 11(2):167-174. https://dx.doi.org/1900/RDS.2014.11.167 The product has detoxifying effects and stimulates the regenerative function of the liver. Administration of Milk Thistle in Cats

Milk Thistle is one of the most effective herbs at stimulating the production and flow of bile, which helps to break down excess fat and prevents it from accumulating in the liver. Bile is also essential for the elimination of toxins in the body. Why Nutramed is the best supplement for older dogs Denamarin may be recommended as part of a treatment plan for a variety of circumstances where the liver is involved. In cats, this can include conditions where liver enzymes are elevated on bloodwork like in cholangitis/cholangiohepatitis syndrome, hepatic lipidosis, and feline triad disease/triaditis. Among the few papers we found with our search criteria, there are also a couple of case reports, in which a combination of active principles was used, including silybin and S-adenosylmethionine: one regarding a cat and one a dog. The former was a young adult female cat presented with acute neurological signs, pyrexia, and increased ALT/GPT, AST/GOT, and bilirubin, diagnosed after a complete diagnostic work up with hepatitis caused by Yersinia pseudotuberculosis. Successful treatment included antimicrobials, combination of S-adenosylmethionine and silybin, and fluid therapy [ 23]. The latter was about an adult female Pug dog diagnosed with toxic hepatopathy, caused by microcystins present in a dietary supplement that was given to the dog. After a very articulated therapeutic protocol including S-adenosylmethionine and silybin, ursodeoxycholic acid, N-acetylcysteine, antimicrobials, dolasetron, metoclopramide, vitamins K and B, and fluids, the cat fully recovered from hepatopathy [ 25]. Milk Thistle is a natural, herbal supplement that is gentle enough for long-term use. Why choose Pet Wellbeing Milk Thistle for your feline friend? Numerous complementary feeds to support liver function are commercially available for small animals. Aiming to furnish a scientific support for clinicians/nutritionists that necessitate a complementary feed to support liver function in dogs and cats, with the present paper, we analyzed scientific evidences supporting the use, for this purpose, of ingredients/additives such as artichoke ( Cynara scolymus), curcumin, dandelion ( Taraxacum officinale), milk thistle ( Silybum marianum), phosphatidylcholine, and S-adenosylmethionine. Although sustained by significant results, our review found only few scientific papers, and albeit we believe that they represent a significant aid in handling hepatopathies, in the authors’ opinion, this topic probably deserves, and would benefit of, further studies. 1. IntroductionMilk thistle is one of the few herbs that have no equivalent in conventional medicine and has many uses. You can read about the many applications of Milk Thistle for cats and dogs on Dr. Hillary Cook's blog. Herbal dietary supplements are beneficial to the health and wellbeing of your pet and are safe for long-term use. Every pet responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next. Natural support for the liver using whole fruit extract. High in silymarin and other active compounds

Here’s the link to our saver kit: https://www.nhvnaturalpetproducts.com/dog-cat-supplements-for-pancreas-imbalance Perhaps a vet prescribed milk thistle would be the safest. There are several choices, including the alcohol-free liquid form. Our research has limitations as it looked only for some molecules, the most frequently included in veterinary complementary feed to support the liver function in dogs and cats, and it consequently failed to meet, for example, some other stimulating research articles always regarding this topic, although in healthy animals (one was an abstract) [ 49, 50] or in form of review [ 51]. In one case, SAMe was administered to healthy cats resulting, among other encouraging effects, in a positive influence on hepatic redox balance [ 50]. The scientific name for milk thistle is Silybum Marianum. It’s also referred to as wild artichoke and holy thistle. Using Milk Thistle for Dogs

As a nutraceutical, Denamarin is not considered a medication, and more of a health supplement for liver support, but it is used very widely in veterinary medicine as an adjunctive treatment for various kinds of liver disease, as well as for pets on long-term medications that may stress or damage liver function over time. Diabetes medications. Milk thistle might lower blood sugar in people who have type 2 diabetes. Closely monitor your blood sugar levels, and talk to your doctor before taking milk thistle supplements if you take diabetes medications. Stephanie, I'd like to ask you, do you have a diagnosis that tells you what kind of liver disease Malcolm has? Also, did he ever have an ultrasound to rule out cancer?