Analysis enhancement - This introspection dominant effect is only manifested consistently in the context of a non-social setting in which the user is alone.

Shulgin considered 2C-B to be one of his greatest inventions; it was one of the six psychedelic molecules among his “magic half dozen,” which he thought had the most potential (and five of which he invented himself). He’s also claimed 2C-B to be one of his all-time favorite psychedelics, which is significant for a scientist who’s gone on around 10,000 psychedelic trips. “It is, in my opinion, one of the most graceful, erotic, sensual, introspective compounds I have ever invented,” he wrote in his “Ask Dr. Shulgin” column in 2003. “For most people, it is a short-lived and comfortable psychedelic with neither toxic side effects nor next-day hangover.” Bakanlar Kurulu Kararı - Karar Sayısı: 2011/1310". Resmî Gazete, Sayı: 27845 (in Turkish). Başbakanlık Mevzuatı Geliştirme ve Yayın Genel Müdürlüğü [General Directorate of Legislation Development and Publication] (published February 13, 2011). January 7, 2011. The second part was made freely available by Shulgin on Erowid while the first part is available only in the printed text. While the reactions described are beyond the ability of people with a basic chemistry education, some tend to emphasize techniques that do not require difficult-to-obtain chemicals. Notable among these are the use of mercury-aluminum amalgam (an unusual but easy to obtain reagent) as a reducing agent and detailed suggestions on legal plant sources of important drug precursors such as safrole.Laughter fits - Anecdotal reports and literature suggest that 2C-B is capable of producing sudden fits of mild to intense laughter. United Kingdom: 2C-B is a Class A drug in the United Kingdom as a result of the phenethylamine catch-all clause. [40] Croatia: 2C-B is illegal to possess, produce and sell in Croatia as a result of it being a 2,5-dimethoxyphenylethanamine. [27] PLUS FOUR (++++) A rare and precious transcendental state, which has been called a ‘peak experience’, a ‘religious experience,’‘divine transformation,’ a ‘state of Samadhi’ and many other names in other cultures. It is not connected to the +1, +2, and +3 of the measuring of a drug’s intensity. It is a state of bliss, a participation mystique, a connectedness with both the interior and exterior universes, which has come about after the ingestion of a psychedelic drug, but which is not necessarily repeatable with a subsequent ingestion of that same drug. If a drug (or technique or process) were ever to be discovered which would consistently produce a plus four experience in all human beings, it is conceivable that it would signal the ultimate evolution, and perhaps the end of, the human experiment. You told me that you invent new psychedelics and that you have a group of people who try them out after you've made sure they're safe and ,/ He interrupted, "Not safe. There is no such thing as safety. Not with drugs and not with anything else. You can only presume relative safety. Too much of anything is unsafe. Too much food, too much drink, too much aspirin, too much anything you can name, is likely to be unsafe."

This impossible to categorize book is ostensibly the story of Alexander Shulgin, a.k.a. “Dr Ecstasy”, the man with the most claim to have actually discovered the drug. It's a hefty tome, half chemistry and half autobiography – the latter part being half written by his wife Anne. The book seems to be largely distributed under the acronym, PIKHAL. Tramadol - Tramadol is well-documented to lower the seizure threshold [20] and psychedelics may act to trigger seizures in susceptible individuals. [ citation needed] Shortly after gaining traction in the underground psychotherapy community, 2C-B became popular in the recreational drug scene. It was well-liked as a MDMA substitute in raves and club parties due to its minimal comedown and a clear, euphoric headspace. Armstrong, B. D.; Paik, E.; Chhith, S.; Lelievre, V.; Waschek, J. A.; Howard, S. G. (October 26, 2004). "Potentiation of (DL)‐3, 4‐methylenedioxymethamphetamine (MDMA)‐induced toxicity by the serotonin 2A receptor partial agonist d‐lysergic acid diethylamide (LSD), and the protection of same by the serotonin 2A/2C receptor antagonist MDL 11,939". Neuroscience Research Communications. 35 (2): 83–95. doi: 10.1002/nrc.20023. eISSN 1520-6769. David Biello (March 20, 2008). "Self-Experimenters: Psychedelic Chemist Explores the Surreality of Inner Space, One Drug at a Time". Scientific American. Nature Publishing Group. eISSN 1946-7087. ISSN 0036-8733 . Retrieved October 10, 2020.Alexander (better known as “Sasha”) and Ann Shulgin’s PiHKAL: A Chemical Love Story has become a foundational work in the genre and was the first book to fully impart the how-to chemistry, and convey the effects, of many of the entheogenic drugs that are currently being studied and used to heal trauma and deal with death.