Silver D, et al. Mastering the game of Go with deep neural networks and tree search. Nature. 2016;529(7587):484–9. You ZH, et al. A MapReduce based parallel SVM for large-scale predicting protein-protein interactions. Neurocomputing. 2014;145:37–43.

An acco t of money due to His Ma y for the 1/3 of seisures and forfeited vessells and goods detained by them, as by sufficient attested vouchers I am ready to make appeare.” Presentment of the Com rs of Customs to the Lords of the Treasury, upon a memorial of the merchants of Bideford touching their bonds for the duty on tobacco; stating that they thought it reasonable to forbear prosecuting the bonds of such merchants as had debentures owing from the public as far as the debts extended, &c. Dated 12 Oct. 1700. Barry, Jonathan. ‘Introduction’, in Jonathan Barry & Christopher Brooks (eds), The Middling Sort of People: Culture, Society and Politics in England , 1550-1800 (London, 1994), pp.1-27. Protein-protein interactions (PPIs) are critical for many biological processes. It is therefore important to develop accurate high-throughput methods for identifying PPI to better understand protein function, disease occurrence, and therapy design. Though various computational methods for predicting PPI have been developed, their robustness for prediction with external datasets is unknown. Deep-learning algorithms have achieved successful results in diverse areas, but their effectiveness for PPI prediction has not been tested. Results My Lords are of opinion that Mr. Devereux hath not made out any one of the articles in his charge ag t M r Baker as to any material point.”All formulations of VECTASHIELD Antifade Mounting Media are available with or without the counterstain DAPI (4', 6-diamidino-2-phenylindole), which produces a blue fluorescence when bound to DNA with excitation at about 360 nm and emission at 460 nm. If desired, the concentration of DAPI can be reduced by mixing with the corresponding VECTASHIELD Mounting Medium (without DAPI). Mr. Granvill's mem ll relating to Mote Park is read. The King will goe no further then the agreem t with the Duke of Albemarle.” You ZH, et al. Predicting protein-protein interactions from primary protein sequences using a novel multi-scale local feature representation scheme and the random forest. PLoS One. 2015;10(5):e0125811.

We thank Youjun Xu, Ziwei Dai, Shuaishi Gao, and other members of the Lai laboratory for insightful and helpful suggestions. Funding Collins SR, et al. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Mol Cell Proteomics. 2007;6(3):439–50. Another petition on the same subject, and a report thereon by the Lord Ranelagh, dated 20 June 1700, from which it appears that the said ensign was killed at Torbay on 23 July 1693. Zhao YO. Predicting Protein-protein Interactions from Protein Sequences Using Probabilistic Neural Network and Feature Combination. Int J Inf Comput Sci. 2014;11(7):2397–406. He might, indeed, make a claim to a considerable quantity of plate, &c., due to him as groom of the stole upon the death of his royal master [Charles II.], which he never received, though it was solemnly promised.Zhang YN, et al. Adaptive compressive learning for prediction of protein-protein interactions from primary sequence. J Theor Biol. 2011;283(1):44–52. Hassell-Smith, A. ‘Labourers in Late Sixteenth-Century England: A Case Study from North Norfolk [Part II], Continuity & Change 4:3 (1989), 367-94. PJF and LLH conceived the study; STL performed the data collection, training, prediction and analysis; STL, PJF and LLH wrote the paper; ZB constructed the server; All authors contributed to the revised and approved the final manuscript. Competing interests